Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC): The Impact of Automated FISH Technology

Line Emilie Boje  Zakariasen; Mary Mathilde Knoblauch Fasting; Sys Johnsen; Svetlana Teplaia; Sanni Charlotte Pedersen; Filis Cramer Necip; Camilla   Qvist

Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC): The Impact of Automated FISH Technology

Line Emilie Boje Zakariasen
, Mary Mathilde Knoblauch Fasting
, Sys Johnsen
, Svetlana Teplaia
, Sanni Charlotte Pedersen
, Filis Cramer Necip
, Camilla Qvist

Publikation: Bidrag til tidsskrift › Tidsskriftsartikel › Forskning › peer review

Abstract

The Met gene, which encodes a receptor tyrosine kinase, is crucial in cancer cell proliferation and survival. Fluorescence in situ hybridization (FISH) is vital for assessing MET-gene amplification in non-small cell lung cancer (NSCLC). Manual FISH assays are time-consuming and results are critical for treatment decision; automation could reduce turnaraound time. This study evaluates the potentional benefits of the automated FISH-system, Oncore Pro X (biocare Medical USA), by assessing factors including results, turnaround time, and cost.

Originalsprog	Engelsk
Tidsskrift	International Journal of Biomedical Laboratory Science
Vol/bind	14
Udgave nummer	1
Sider (fra-til)	24-38
ISSN	2308-7706
Status	Udgivet - 2025

Citationsformater

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title = "Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC): The Impact of Automated FISH Technology",

abstract = "The Met gene, which encodes a receptor tyrosine kinase, is crucial in cancer cell proliferation and survival. Fluorescence in situ hybridization (FISH) is vital for assessing MET-gene amplification in non-small cell lung cancer (NSCLC). Manual FISH assays are time-consuming and results are critical for treatment decision; automation could reduce turnaraound time. This study evaluates the potentional benefits of the automated FISH-system, Oncore Pro X (biocare Medical USA), by assessing factors including results, turnaround time, and cost.",

author = "Zakariasen, \{Line Emilie Boje\} and Fasting, \{Mary Mathilde Knoblauch\} and Sys Johnsen and Svetlana Teplaia and Pedersen, \{Sanni Charlotte\} and Necip, \{Filis Cramer\} and Camilla Qvist",

year = "2025",

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Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC): The Impact of Automated FISH Technology. / Zakariasen, Line Emilie Boje ; Fasting, Mary Mathilde Knoblauch; Johnsen, Sys et al.
I: International Journal of Biomedical Laboratory Science , Bind 14, Nr. 1, 2025, s. 24-38.

Publikation: Bidrag til tidsskrift › Tidsskriftsartikel › Forskning › peer review

TY - JOUR

T1 - Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC)

T2 - The Impact of Automated FISH Technology

AU - Zakariasen, Line Emilie Boje

AU - Fasting, Mary Mathilde Knoblauch

AU - Johnsen, Sys

AU - Teplaia, Svetlana

AU - Pedersen, Sanni Charlotte

AU - Necip, Filis Cramer

AU - Qvist, Camilla

PY - 2025

Y1 - 2025

N2 - The Met gene, which encodes a receptor tyrosine kinase, is crucial in cancer cell proliferation and survival. Fluorescence in situ hybridization (FISH) is vital for assessing MET-gene amplification in non-small cell lung cancer (NSCLC). Manual FISH assays are time-consuming and results are critical for treatment decision; automation could reduce turnaraound time. This study evaluates the potentional benefits of the automated FISH-system, Oncore Pro X (biocare Medical USA), by assessing factors including results, turnaround time, and cost.

AB - The Met gene, which encodes a receptor tyrosine kinase, is crucial in cancer cell proliferation and survival. Fluorescence in situ hybridization (FISH) is vital for assessing MET-gene amplification in non-small cell lung cancer (NSCLC). Manual FISH assays are time-consuming and results are critical for treatment decision; automation could reduce turnaraound time. This study evaluates the potentional benefits of the automated FISH-system, Oncore Pro X (biocare Medical USA), by assessing factors including results, turnaround time, and cost.

M3 - Journal article

SN - 2308-7706

VL - 14

SP - 24

EP - 38

JO - International Journal of Biomedical Laboratory Science

JF - International Journal of Biomedical Laboratory Science

IS - 1

ER -

Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC): The Impact of Automated FISH Technology

Abstract

Fingeraftryk

Citationsformater